What’s the canonical way to pronounce ICLR?
Samuele Marro from the University of Oxford has been taking a data-driven approach.

Samuele Marro's data gathering project
So far, the results are largely in favour of “eye-clear” over “I-C-L-R”.
Update (29 April): at the final count, it’s 526 for “eye-clear” vs 245 for “I-C-L-R”. A victory for “eye-clear”, though almost a third of voters preferred the letter-based pronunciation.